3,426 research outputs found

    Games the Government Plays: Federal Funding of Minority Economic Development

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    The objective of this study was to investigate regional differences in injury incidence in men's professional football in Europe. A nine-season prospective cohort study was carried out between 2001–2002 and 2009–2010 involving 1357 players in 25 teams from nine countries. Teams were categorized into different regions according to the Köppen–Geiger climate classification system. Teams from the northern parts of Europe (n = 20) had higher incidences of injury overall [rate ratio 1.12, 95% confidence interval (CI) 1.06 to 1.20], training injury (rate ratio 1.16, 95% CI 1.05 to 1.27), and severe injury (rate ratio 1.29, 95% CI 1.10 to 1.52), all statistically significant, compared to teams from more southern parts (n  = 5). In contrast, the anterior cruciate ligament injury incidence was lower in the northern European teams with a statistically significant difference (rate ratio 0.43, 95% CI 0.25 to 0.77), especially for noncontact anterior cruciate ligament injury (rate ratio 0.19, 95% CI 0.09 to 0.39). In conclusion, this study suggests that there are regional differences in injury incidence of European professional football. However, further studies are needed to identify the underlying causes.Funding Agencies|UEFA Football Development Division||Swedish National Centre for Research in Sports||</p

    Response to ‘Adiponectin in chronic kidney disease: Dr Jekyll and Mr Hyde’

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    CONODONTS OF THE LOWERMOST TRIASSIC OF SPITI, AND NEW ZONATION BASED ON NEOGONDOLELLA SUCCESSIONS

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    Conodonts from the lowermost Triassic Otoceras woodwardi beds and adjacent strata of Spiti are described and compared with Permian-Triassic (P-T) boundary bed faunas from elsewhere. A new pelagic zonation based on Neogondolella is introduced: the interval characterized by N. carinata-N. taylorae is subdivided into three parts based on successive first appearances of N. meishanensis, N. krystyni Orchard n. sp. and N. discreta Orchard and Krystyn n. sp., the nominal species of three successive zones. The development of these Griesbachian species involves a progressive morphological change in the configuration of the axial part (blade-carina-cusp) of the pectiniform elements. The pelagic conodont zonation is intercalibrated with the parallel zonation based on species of Hindeodus and Isarcicella, and with ammonoid faunas from Spiti, other Himalayan localities, and the Arctic. The meishanensis Zone embraces the parvus Zone and part of the overlying staeschei Zone. Strata containing O. woodwardi in Spiti carry the indices to the staeschei and krystyni zones. The Neogondolella conodont fauna associated with Otoceras differs from that of the latest Permian Changshing Limestone of China, but resembles that from the P-T boundary transition beds at Meishan, where a meishanensis Zone of restricted scope occurs beneath the parvus datum. The faunal change which introduces the characteristic Neogondolella species of the N. carinata-N. taylorae fauna occurs at the base of the P-T boundary transition beds at Meishan, the proposed boundary stratotype. Slightly above this level, the disappearance of most Neogondolella species and the introduction of new Hindeodus species coincides with a change in conodont biofacies rather than an extinction event. In the Spiti sections, the N. carinata-N. taylorae fauna, associated at first with H. parvus (as in Selong, Tibet), persists through the entire Griesbachian. Indices of the three Neogondolella zones are also recognized in the Salt Range and the Canadian Arctic. Four new conodont species are described: Neogondolella discreta, N. kazi, N. krystyni, and N. nassichuki.&nbsp

    Static stretching of the hamstring muscle for injury prevention in football codes: a systematic review

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    Purpose: Hamstring injuries are common among football players. There is still disagreement regarding prevention. The aim of this review is to determine whether static stretching reduces hamstring injuries in football codes. Methods: A systematic literature search was conducted on the online databases PubMed, PEDro, Cochrane, Web of Science, Bisp and Clinical Trial register. Study results were presented descriptively and the quality of the studies assessed were based on Cochrane’s ‘risk of bias’ tool. Results: The review identified 35 studies, including four analysis studies. These studies show deficiencies in the quality of study designs. Conclusion: The study protocols are varied in terms of the length of intervention and follow-up. No RCT studies are available, however, RCT studies should be conducted in the near future

    Intercalibration of Boreal and Tethyan timescales: the magneto-biostratigraphy of the Middle Triassic and the latest Early Triassic from Spitsbergen, Arctic Norway

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    An integrated bio-magnetostratigraphic study of the latest Early Triassic to the upper parts of the Middle Triassic, at Milne Edwardsfjellet in central Spitsbergen, Svalbard, allows a detailed correlation of Boreal and Tethyan biostratigraphies. The biostratigraphy consists of ammonoid and palynomorph zonations, supported by conodonts, through some 234 m of succession in two adjacent sections. The magnetostratigraphy consists of ten substantive normal–reverse polarity chrons defined by sampling at 150 stratigraphic levels. The magnetization is carried by magnetite and an unidentified magnetic sulphide, and is difficult to fully separate from a strong present-day like magnetization. The bio-magnetostratigraphy from the late Olenekian (Vendomdalen Member) is supplemented by data from nearby Vikinghøgda. The early and mid-Anisian has a high sedimentation rate, comprising over half the ca. 140-m thickness of the Botneheia Formation, whereas the late Anisian and lower Ladinian is condensed into about 20 m. The two latest Boreal Ladinian ammonoid zones are absent due to erosional truncation below the Tschermakfjellet Formation. Correlation to Tethyan bio-magnetostratigraphies shows the traditional base of the Boreal Anisian (base of G. taimyrensis Zone) precedes the base Anisian (using here definitions based on the Desli Caira section in Romania). The Boreal upper Anisian G. rotelliforme and F. nevadanus ammonoid zones correlate to most of the Tethyan Pelsonian and Illyrian substages. The base Ladinian defined in the Tethyan global boundary stratotype and point (GSSP) is closely equivalent to the traditional base of the Boreal Ladinian at the I. oleshkoi Zone. The latest Olenekian to early Anisian magnetic polarity timescale is refined using the Spitsbergen data

    A prospective analysis of the injury incidence of young male professional football players on artificial turf

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    Background: The effects of synthetic surfaces on the risk of injuries is still debated in literature and the majority of published data seems to be contradictory. For such reasons the understanding of injury incidence on such surfaces, especially in youth sport, is fundamental for injury prevention. Objectives: The aim of this study was to prospectively report the epidemiology of injuries in young football players, playing on artificial turfs, during a one sports season. Patients and Methods: 80 young male football players (age 16.1 ± 3.7 years; height 174 ± 6.6 cm; weight 64.2 ± 6.3 kg) were enrolled in a prospective cohort study. The participants were then divided in two groups; the first included players age ranging from 17 to 19 (OP) whereas the second included players age ranging from 13 to 16 (YP). Injury incidence was recorded prospectively, according to the consensus statement for soccer. Results: A total of 107 injuries (35 from the OP and 72 from the YP) were recorded during an exposure time of 83.760 hours (incidence 1.28/1000 per player hours); 22 during matches (incidence 2.84/1000 per player hours, 20.5%) and 85 during training (incidence 1.15/1000 per player hours, 79.5%). Thigh and groin were the most common injury locations (33.6% and 21.5%, respectively) while muscle injuries such as contractures and strains were the most common injury typologies (68.23%). No statistical differences between groups were displayed, except for the rate of severe injuries during matches, with the OP displaying slightly higher rates compared to the YP. Severe injuries accounted for 10.28% of the total injuries reported. The average time lost due to injuries was 14 days. Re-injuries accounted for 4.67% of all injuries sustained during the season. Conclusions: In professional youth soccer injury rates are reasonably low. Muscle injuries are the most common type of injuries while groin and thigh the most common locations. Artificial turf pitches don’t seem to contribute to injury incidence in young football players

    Elevated cerebral spinal fluid biomarkers in children with mucopolysaccharidosis I-H.

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    Mucopolysaccharidosis (MPS) type-IH is a lysosomal storage disease that results from mutations in the IDUA gene causing the accumulation of glycosaminoglycans (GAGs). Historically, children with the severe phenotype, MPS-IH (Hurler syndrome) develop progressive neurodegeneration with death in the first decade due to cardio-pulmonary complications. New data suggest that inflammation may play a role in MPS pathophysiology. To date there is almost no information on the pathophysiologic changes within the cerebral spinal fluid (CSF) of these patients. We evaluated the CSF of 25 consecutive patients with MPS-IH. While CSF glucose and total protein were within the normal range, we found a significantly mean elevated CSF opening pressure at 24 cm H2O (range 14-37 cm H2O). We observed a 3-fold elevation in CSF heparan sulfate and a 3-8 fold increase in MPS-IH specific non-reducing ends, I0S0 and I0S6. Cytokine analyses in CSF of children with MPS-IH showed significantly elevated inflammatory markers including: MCP-1 SDF-1a, IL-Ra, MIP-1b, IL-8, and VEGF in comparison to unaffected children. This is the largest report of CSF characteristics in children with MPS-IH. Identification of key biomarkers may provide further insight into the inflammatory-mediated mechanisms related to MPS diseases and perhaps lead to improved targeted therapies

    77: Impact of Ribavirin Therapy on Respiratory Syncitial Virus Infection Following Hematopoietic Cell Transplantation

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